Model

The VA Core Model is a domain-agnostic model for representing scientific knowledge about genetic variation, and the evidence and provenance supporting it.

A hierarchical view of the VA Core Model is below. See the Modeling Foundations section for an overview of modeling principles and patterns that govern its use.

Legend: Hierarchical structure of classes and attributes comprising the domain-agnostic VA Core Model. Simple classes for representing Domain Entities such Conditions and Therapies are defined in the VA Core Model, but are not shown here.

Links below (or menu to the left) provide detailed information about the attributes of each class, and guidance for their use.

VA Core Model Classes

• Entity
  • Agent
  • Contribution
  • Data Item
  • Data Set
  • Document
  • Evidence Line
  • Genetic Context Variant Proposition
  • Information Entity
  • Mappable Concept
  • Method
  • Proposition
  • Statement
    • Data Structure
    • Implementation Guidance
      • 1. Statement and Proposition Semantics
      • 2. Attaching Evidence to a Statement
      • 3. Use of the Proposition.qualifier Attribute:
  • Study Group
  • Study Result
  • Subject Variant Proposition
• Element
  • Coding
  • Concept Mapping
  • Extension
• Data Types
  • code
  • date
  • datetime
  • iriReference
• Domain Entities
  • Condition
  • Condition Set
  • Gene
  • Therapy
  • Therapy Group
  • Variation